Potentiometric Probes

We are the VSD experts.

VSD Primer PDF with Discount Code for Your Next Order!

Includes topics from radiometric imaging to dye toxicity with hopefully something to help experts and newcomers alike get the most from their voltage imaging experiments.

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What We Do

Potentiometric Probes develops and supplies voltage-sensitive dyes (VSDs) for academic and pharmaceutical industry researchers. These fluorescent dyes are used to stain cells, tissues, and whole organs and allow electrical activity of the brain and heart to be studied optically using microscopes. Voltage-sensitive dyes are used in basic research, as well as for drug discovery and cardiac safety screening of developmental drugs.

What’s Next?

Potentiometric Probes is developing new VSD technology that promises to have a rapid response as well as high sensitivity for the highest resolution and most informative optical voltage recordings possible.

News

Our Products

Voltage-sensitive dyes such as Di-4-ANEPPS bind to cell membranes and translate voltage changes in cells to changes in fluorescence. You can view all of our classic, fluorinated, and long-wavelength dyes on our product page. 

Product Overview
Membrane binding of voltage-sensitive dyes from Potentiometric Probes including Di-4-ANEPPS

Our Research

 
Neuro Research
Arrhythmia in live pig heart seen with voltage-sensitive dye, Peter Lee
Cardiac Research
Voltage-sensitive dyes like Di-4-ANEPPS for high throughput screening, cardiac toxicity.
High Throughput Screening
Arrhythmia in live pig heart seen with voltage-sensitive dye, Peter Lee
TMRE & TMRM